Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.49 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977743 | 0.90 | MAPT (0.54) | MAPTMAPK14RAB9AMEN1LMNA | |
| SCHEMBL7991876 | 0.88 | NPBWR1 (0.59) | MAPTMAPK14RAB9AMEN1LMNA | |
| SCHEMBL7991834 | 0.86 | MAPK14 (0.61) | MAPTMAPK14RAB9AMEN1LMNA | |
| SCHEMBL7988678 | 0.86 | MAPK14 (0.61) | MAPTMAPK14RAB9AMEN1LMNA | |
| SCHEMBL7988654 | 0.86 | MMP2 (0.57) | MAPTMAPK14RAB9AMEN1LMNA | |
| SCHEMBL7992002 | 0.85 | MAPK13 (0.60) | MAPTMAPK14MEN1KMT2AMAPK13 | |
| SCHEMBL7977732 | 0.84 | MAPT (0.56) | MAPTMAPK14RAB9AMEN1LMNA | |
| SCHEMBL7977380 | 0.84 | MEN1 (0.56) | MAPTMAPK14RAB9AMEN1LMNA | |
| SCHEMBL7991922 | 0.84 | AR (0.50) | MAPTMAPK14RAB9AMEN1LMNA | |
| SCHEMBL6366542 | 0.84 | MAPK13 (0.59) | MAPTMAPK14KMT2AMAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |