SCHEMBL31030614

SCHEMBL31030614

CC(=O)c1cnn2c(-c3ccc(C#N)cc3)cccc12

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ EGLN2 Q96KS0 18/20 0.52
▸ TLR8 Q9NR97 1/20 0.50
▸ MKNK1 Q9BUB5 1/20 0.40
▸ MKNK2 Q9HBH9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31030739 0.81 EGLN2 (0.51) EGLN2TLR8MKNK1MKNK2
SCHEMBL31030637 0.78 MKNK1 (0.42) EGLN2TLR8MKNK1MKNK2
SCHEMBL31030694 0.78 EGLN2 (0.49) EGLN2TLR8
SCHEMBL17453430 0.72 EIF4A3 (0.43) —
SCHEMBL31030641 0.70 TLR8 (0.46) EGLN2TLR8MKNK1MKNK2
SCHEMBL31030459 0.68 EGLN2 (0.42) EGLN2TLR8MKNK1MKNK2
SCHEMBL3684977 0.68 PIK3CD (0.47) —
SCHEMBL17454510 0.68 ALDH1A1 (0.37) —
SCHEMBL16248945 0.67 EGLN2 (1.00) EGLN2
SCHEMBL20646791 0.67 MAPK1 (0.66) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4653437-A2 NOVEL HETEROCYCLIC COMPOUNDS Innovo Therapeutics Inc. (KR) 2025-11-26 — — EP claimed
EP-4653437-A2 NOVEL HETEROCYCLIC COMPOUNDS Innovo Therapeutics Inc. (KR) 2025-11-26 — — EP disclosed
WO-2024154979-A2 NOVEL HETEROCYCLIC COMPOUNDS 주식회사 이노보테라퓨틱스 2024-07-25 — — WO disclosed
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