SCHEMBL31030795

SCHEMBL31030795

CC1OC(c2ccccc2)=NC1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.46
DRD4 P21917 1/20 0.46
DRD3 P35462 1/20 0.46
USP1 O94782 1/20 0.41
WDR48 Q8TAF3 1/20 0.41
MMP9 P14780 4/20 0.41
HTR1D P28221 1/20 0.34
HTR2C P28335 1/20 0.34
HTR2B P41595 1/20 0.34
HTR3A P46098 1/20 0.34
MAOB P27338 4/20 0.34
MMP1 P03956 1/20 0.33
ALOX15 P16050 1/20 0.33
LMNA P02545 1/20 0.32
KMT2A Q03164 2/20 0.31
FUCA1 P04066 1/20 0.31
MEN1 O00255 1/20 0.31
RAB9A P51151 1/20 0.31
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9886168 0.80 DRD2 (0.48) DRD2DRD4DRD3USP1WDR48
SCHEMBL13495003 0.80 DRD2 (0.48) DRD2DRD4DRD3USP1WDR48
SCHEMBL15304894 0.80 DRD2 (0.48) DRD2DRD4DRD3USP1WDR48
SCHEMBL11128470 0.77 DRD2 (0.43) DRD2DRD4DRD3USP1WDR48
SCHEMBL4354314 0.77 DRD2 (0.43) DRD2DRD4DRD3USP1WDR48
SCHEMBL11128460 0.77 DRD2 (0.43) DRD2DRD4DRD3USP1WDR48
SCHEMBL14396694 0.76 DRD2 (0.55) DRD2DRD4DRD3USP1WDR48
SCHEMBL14455076 0.76 DRD2 (0.55) DRD2DRD4DRD3USP1WDR48
SCHEMBL14564526 0.76 USP1 (0.47) DRD2DRD4DRD3USP1WDR48
SCHEMBL12713489 0.76 DRD2 (0.55) DRD2DRD4DRD3USP1WDR48

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118653158-A Synthesis and application of 4-oxo-oxazoline compound 西北师范大学 2024-09-17 CN disclosed