Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.56 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.53 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.52 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | ACP1 | P24666 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229472 | 0.88 | MRGPRX4 (0.69) | MRGPRX4PTGER1S1PR5HPGDRAB9A | |
| SCHEMBL29557477 | 0.86 | HPGD (0.59) | MRGPRX4PTGER1GLRA1NPC1HPGD | |
| SCHEMBL1599431 | 0.86 | HPGD (0.59) | MRGPRX4PTGER1GLRA1NPC1HPGD | |
| SCHEMBL5457607 | 0.86 | MRGPRX4 (0.54) | MRGPRX4PTGER1S1PR5NPC1HPGD | |
| SCHEMBL2744895 | 0.85 | PARP10 (0.59) | MRGPRX4PTGER1S1PR5NPC1HPGD | |
| SCHEMBL4747320 | 0.85 | MAOB (0.59) | MRGPRX4PTGER1S1PR5NPC1HPGD | |
| SCHEMBL8512033 | 0.84 | SLC6A2 (0.57) | MRGPRX4PTGER1S1PR5NPC1HPGD | |
| SCHEMBL9341900 | 0.84 | NPC1 (0.54) | MRGPRX4PTGER1S1PR5NPC1HPGD | |
| SCHEMBL8756076 | 0.84 | MRGPRX4 (0.61) | MRGPRX4PTGER1GLRA1NPC1HPGD | |
| SCHEMBL4161097 | 0.83 | NPC1 (0.53) | MRGPRX4PTGER1S1PR5NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240254135-A1 | POLYPHENOL COMPOUNDS | EPIRIUM BIO INC (US) | 2024-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240254135-A1 | POLYPHENOL COMPOUNDS | COMT, MAPT, PPARG | MRGPRX4 4823/4885PTGER1 2493/4885S1PR5 4213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.