Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | RXRA | P19793 | 2/20 | 0.51 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1599431 | 1.00 | HPGD (0.59) | HPGDNPC1RAB9ASMN1; SMN2SMPD1 | |
| SCHEMBL3944668 | 0.95 | MRGPRX4 (0.59) | HPGDNPC1RAB9ASMN1; SMN2SMPD1 | |
| SCHEMBL7861369 | 0.92 | HPGD (0.52) | HPGDNPC1RAB9ASMN1; SMN2SMPD1 | |
| SCHEMBL184987 | 0.91 | SMPD1 (0.71) | HPGDNPC1RAB9ASMN1; SMN2SMPD1 | |
| SCHEMBL341137 | 0.91 | NPC1 (0.73) | HPGDNPC1RAB9ASMN1; SMN2SMPD1 | |
| SCHEMBL13434464 | 0.88 | SMPD1 (0.57) | HPGDNPC1RAB9ASMN1; SMN2SMPD1 | |
| SCHEMBL8756076 | 0.88 | MRGPRX4 (0.61) | HPGDNPC1RAB9ASMN1; SMN2HDAC6 | |
| SCHEMBL29556736 | 0.87 | MRGPRX4 (0.62) | HPGDNPC1RAB9ASMN1; SMN2SMPD1 | |
| SCHEMBL1600077 | 0.87 | MRGPRX4 (0.62) | HPGDNPC1RAB9ASMN1; SMN2SMPD1 | |
| SCHEMBL71526 | 0.86 | RXRA (0.58) | HPGDNPC1RAB9ASMN1; SMN2SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118598807-A | Application of polyphenol derivative prodrug compound in preparation of sucrose acetate isobutyrate long-acting slow-release in-situ gel | 沈阳药科大学 | 2024-09-06 | — | — | CN | disclosed |
| CN-114423766-A | Penicilliane derivatives for the treatment of bacterial infections | 丹诺医药(苏州）有限公司 | 2022-04-29 | — | — | CN | disclosed |