Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5579490 | 0.77 | PKM (0.47) | PDE10AKDM4EHSD17B10MAPTTP53 | |
| SCHEMBL29822663 | 0.74 | KDM4E (0.46) | PDE10AKDM4EHSD17B10MAPTTP53 | |
| SCHEMBL537413 | 0.72 | SMN1; SMN2 (0.52) | KDM4EHSD17B10MAPTTP53POLB | |
| SCHEMBL31021114 | 0.72 | SMN1; SMN2 (0.52) | KDM4EHSD17B10MAPTTP53POLB | |
| SCHEMBL5001588 | 0.72 | KDM4E (0.54) | PDE10AKDM4EHSD17B10MAPTTP53 | |
| Hydrochloric Acid SCHEMBL537827 | 0.71 | SMN1; SMN2 (0.50) | KDM4EHSD17B10MAPTTP53POLB | |
| Hydrochloric Acid SCHEMBL537828 | 0.71 | SMN1; SMN2 (0.50) | KDM4EHSD17B10MAPTTP53POLB | |
| SCHEMBL22342408 | 0.70 | CYP2A6 (0.41) | KDM4EHSD17B10MAPTLMNAALDH1A1 | |
| SCHEMBL22354956 | 0.68 | KDM4E (0.45) | PDE10AKDM4EHSD17B10MAPTTP53 | |
| SCHEMBL824377 | 0.68 | KDM4E (0.47) | KDM4EHSD17B10MAPTTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658651-A1 | NOVEL COMPOUNDS FOR TAU IMAGING | Eli Lilly and Company (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163546-A1 | NOVEL COMPOUNDS FOR TAU IMAGING | ELI LILLY AND COMPANY (US) | 2024-08-08 | — | — | WO | disclosed |