Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 7/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31031237 | 0.93 | CYP2D6 (0.38) | CYP2D6CYP1A2IKBKBSMPD3MAPT | |
| SCHEMBL31031239 | 0.81 | CYP2D6 (0.44) | CYP2D6CYP1A2IKBKBMAPTKMT2A | |
| SCHEMBL18838768 | 0.74 | CYP2D6 (0.40) | CYP2D6CYP1A2IKBKBMAPTKMT2A | |
| SCHEMBL1410648 | 0.71 | CYP2D6 (0.45) | CYP2D6CYP1A2KMT2AMEN1HSD11B1 | |
| SCHEMBL7964234 | 0.68 | CYP2D6 (0.53) | CYP2D6CYP1A2MAPTTDP1KMT2A | |
| SCHEMBL8630790 | 0.68 | CYP2D6 (0.53) | CYP2D6CYP1A2MAPTTDP1KMT2A | |
| SCHEMBL7966928 | 0.68 | CYP2D6 (0.53) | CYP2D6CYP1A2MAPTTDP1KMT2A | |
| SCHEMBL2405904 | 0.67 | CYP2D6 (0.52) | CYP2D6CYP1A2SMPD3MAPTKMT2A | |
| SCHEMBL2405905 | 0.67 | CYP2D6 (0.52) | CYP2D6CYP1A2SMPD3MAPTKMT2A | |
| SCHEMBL15718847 | 0.66 | CYP2D6 (0.46) | CYP2D6CYP1A2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658651-A1 | NOVEL COMPOUNDS FOR TAU IMAGING | Eli Lilly and Company (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163546-A1 | NOVEL COMPOUNDS FOR TAU IMAGING | ELI LILLY AND COMPANY (US) | 2024-08-08 | — | — | WO | disclosed |