Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2405905 | 1.00 | CYP2D6 (0.52) | CYP2D6CYP1A2MAPTMEN1KMT2A | |
| SCHEMBL7966928 | 0.76 | CYP2D6 (0.53) | CYP2D6CYP1A2MAPTMEN1KMT2A | |
| SCHEMBL8630790 | 0.76 | CYP2D6 (0.53) | CYP2D6CYP1A2MAPTMEN1KMT2A | |
| SCHEMBL7964234 | 0.76 | CYP2D6 (0.53) | CYP2D6CYP1A2MAPTMEN1KMT2A | |
| SCHEMBL3388527 | 0.76 | CYP2D6 (0.74) | CYP2D6CYP1A2KMT2AHTR2AHTR2C | |
| SCHEMBL420300 | 0.76 | CYP2D6 (0.74) | CYP2D6CYP1A2KMT2AHTR2AHTR2C | |
| SCHEMBL9705253 | 0.73 | CYP2D6 (0.89) | CYP2D6CYP1A2MAPTMEN1KMT2A | |
| SCHEMBL8531228 | 0.71 | CYP2D6 (0.63) | CYP2D6CYP1A2MEN1KMT2AHTR2A | |
| SCHEMBL20594955 | 0.71 | CYP2D6 (0.59) | CYP2D6CYP1A2MAPTMEN1KMT2A | |
| SCHEMBL3235232 | 0.71 | CYP2D6 (0.59) | CYP2D6CYP1A2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212950-A1 | 4,4-DISUBSTITUTED PIPERIDINES | NOVARTIS AG (CH) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212950-A1 | 4,4-DISUBSTITUTED PIPERIDINES | REN, AGTR2, AVPR2 | CYP2D6 55/4885CYP1A2 115/4885MAPT 3847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.