Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31031215 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL14685289 | 0.69 | CYP2C9 (0.39) | KDM4EALDH1A1PTPN1SMN1; SMN2CYP2C9 | |
| SCHEMBL15767382 | 0.68 | CYP2C9 (0.38) | KDM4EALDH1A1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL31031242 | 0.68 | KDM4E (0.43) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL18867171 | 0.67 | IKBKB (0.43) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL13073711 | 0.65 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL12296332 | 0.65 | CYP2C9 (0.38) | KDM4EALDH1A1POLBGAASMN1; SMN2 | |
| SCHEMBL12638559 | 0.65 | MAP3K14 (0.38) | ALDH1A1GAAHPGDMAPTCYP2C9 | |
| SCHEMBL23917391 | 0.64 | KDM4E (0.59) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL14685300 | 0.64 | PARP1 (0.40) | KDM4EALDH1A1GLAPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658651-A1 | NOVEL COMPOUNDS FOR TAU IMAGING | Eli Lilly and Company (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163546-A1 | NOVEL COMPOUNDS FOR TAU IMAGING | ELI LILLY AND COMPANY (US) | 2024-08-08 | — | — | WO | disclosed |