Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31031242 | 0.87 | KDM4E (0.43) | KDM4EGAAALDH1A1GLAPOLB | |
| SCHEMBL31031253 | 0.77 | KDM4E (0.50) | KDM4EGAAALDH1A1GLAPOLB | |
| SCHEMBL21622748 | 0.77 | KDM4E (0.66) | KDM4EGAAALDH1A1GLAPOLB | |
| SCHEMBL30973203 | 0.69 | IKBKB (0.45) | KDM4EGAAALDH1A1GLAPOLB | |
| SCHEMBL25824093 | 0.69 | IKBKB (0.45) | KDM4EGAAALDH1A1GLAPOLB | |
| SCHEMBL15207705 | 0.68 | PARP1 (0.38) | KDM4EGAAALDH1A1GLAPOLB | |
| SCHEMBL19714762 | 0.68 | KDM4E (0.37) | KDM4EGAAALDH1A1GLAPOLB | |
| SCHEMBL19714789 | 0.68 | ALDH1A1 (0.45) | KDM4EGAAALDH1A1GLAPOLB | |
| SCHEMBL31031245 | 0.66 | KDM4E (0.38) | KDM4EGAAALDH1A1GLAPOLB | |
| SCHEMBL4539855 | 0.66 | SMN1; SMN2 (0.58) | KDM4EGAAALDH1A1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658651-A1 | NOVEL COMPOUNDS FOR TAU IMAGING | Eli Lilly and Company (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163546-A1 | NOVEL COMPOUNDS FOR TAU IMAGING | ELI LILLY AND COMPANY (US) | 2024-08-08 | — | — | WO | disclosed |