Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ASPH | Q12797 | 3/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 6/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4A | O75164 | 2/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30236847 | 0.85 | LMNA (0.44) | LMNAKDM4EASPHKDM8TDP1 | |
| SCHEMBL29272402 | 0.84 | KDM4E (0.41) | LMNAKDM4EASPHKDM8TDP1 | |
| SCHEMBL1554576 | 0.76 | LMNA (0.47) | LMNAKDM4EASPHKDM8TDP1 | |
| SCHEMBL16475154 | 0.76 | LMNA (0.47) | LMNAKDM4EASPHKDM8TDP1 | |
| SCHEMBL6122624 | 0.76 | KDM4E (0.59) | LMNAKDM4EASPHKDM8TDP1 | |
| SCHEMBL17813592 | 0.75 | LMNA (0.50) | LMNAKDM4EASPHKDM8TDP1 | |
| SCHEMBL29084258 | 0.75 | NAPRT (0.55) | LMNAKDM4EASPHKDM8TDP1 | |
| SCHEMBL25405415 | 0.74 | LMNA (0.43) | LMNAKDM4EASPHKDM8TDP1 | |
| SCHEMBL29272315 | 0.74 | PSMD14 (0.39) | LMNAKDM4ETDP1KDM5AKDM4C | |
| SCHEMBL6121797 | 0.71 | KDM4E (0.41) | LMNAKDM4EASPHKDM8TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159537-A | 6-Aza-quinoline derivatives and related uses | 黑钻治疗公司 | 2024-06-07 | — | — | CN | disclosed |