Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL892677 | 0.78 | SCD (0.48) | MEN1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL31032840 | 0.75 | MAPK14 (0.43) | MEN1KMT2AHSP90AA1HSP90AB1MAPT | |
| SCHEMBL11568178 | 0.74 | ALDH1A1 (0.47) | MEN1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL31032976 | 0.74 | MAPK14 (0.44) | MEN1KMT2AHSP90AA1MAPTSMN1; SMN2 | |
| SCHEMBL15121199 | 0.74 | ALDH1A1 (0.70) | ALDH1A1 | |
| SCHEMBL892581 | 0.73 | MAPT (0.50) | MEN1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL434805 | 0.73 | MEN1 (0.61) | MEN1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL1090847 | 0.72 | THRB (0.59) | MEN1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL162619 | 0.72 | CYP1A2 (0.50) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL31286841 | 0.72 | CYP1A2 (0.50) | MEN1KMT2AMAPTALDH1A1ACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240343710-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | 1CBIO, INC. | 2024-10-17 | — | — | US | disclosed |
| WO-2024178127-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | 1CBIO, INC. (US) | 2024-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240343710-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | PARP1, PARP11, PARP12 | MEN1 2494/4885KMT2A 1465/4885HSP90AA1 2878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.