Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 20/20 | 1.00 |
| ▸ | F13A1 | P00488 | 2/20 | 0.67 |
| ▸ | TGM1 | P22735 | 2/20 | 0.67 |
| ▸ | TGM6 | O95932 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22895108 | 1.00 | TGM2 (1.00) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL19463642 | 0.92 | TGM2 (1.00) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL22895107 | 0.92 | TGM2 (1.00) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL22895106 | 0.87 | TGM2 (1.00) | TGM2 | |
| SCHEMBL31032974 | 0.87 | TGM2 (1.00) | TGM2 | |
| SCHEMBL15619631 | 0.86 | TGM2 (1.00) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL19480311 | 0.86 | TGM2 (1.00) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL29359298 | 0.86 | TGM2 (1.00) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL19463817 | 0.86 | TGM2 (1.00) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL22895148 | 0.86 | TGM2 (1.00) | TGM2F13A1TGM1TGM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442533-B1 | TG2 INHIBITOR COMPOUNDS AND USES THEREOF | UNIV OTTAWA (CA) | 2024-08-07 | — | — | EP | disclosed |