Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 8/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31033149 | 0.86 | ALDH1A1 (0.52) | TP53ALDH1A1KDM1AMAPT | |
| SCHEMBL31033189 | 0.77 | DRD2 (0.64) | TP53ALDH1A1DRD2DRD3 | |
| SCHEMBL8853435 | 0.77 | DRD2 (0.50) | TP53ALDH1A1DRD2DRD3MAPT | |
| SCHEMBL11197723 | 0.77 | KDM1A (0.57) | TP53ALDH1A1KDM1ADRD2DRD3 | |
| SCHEMBL5112508 | 0.77 | MEN1 (0.60) | TP53MAPTMEN1KMT2ATHRB | |
| SCHEMBL1764027 | 0.77 | MEN1 (0.48) | TP53ALDH1A1DRD2DRD3MAPT | |
| SCHEMBL13305180 | 0.76 | KDM1A (0.74) | KDM1A | |
| SCHEMBL31033213 | 0.76 | DRD2 (0.56) | TP53ALDH1A1DRD2DRD3MEN1 | |
| SCHEMBL6712910 | 0.76 | DRD2 (0.48) | KDM1ADRD2DRD3 | |
| SCHEMBL6542687 | 0.76 | MEN1 (0.50) | TP53MAPTMEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024163956-A2 | SIGMA RECEPTOR LIGAND COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-08-08 | — | — | WO | disclosed |