Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 13/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21713031 | 1.00 | KLKB1 (0.45) | KLKB1POLBMAPTGRM2ACACB | |
| SCHEMBL21712913 | 0.88 | KLKB1 (0.47) | KLKB1BTK | |
| SCHEMBL23469581 | 0.87 | KLKB1 (0.56) | KLKB1POLBMAPTGRM2ACACB | |
| Lithium Ion SCHEMBL31033178 | 0.87 | KLKB1 (0.48) | KLKB1BTK | |
| SCHEMBL21713014 | 0.85 | KLKB1 (0.59) | KLKB1 | |
| SCHEMBL30140690 | 0.85 | KLKB1 (0.59) | KLKB1 | |
| SCHEMBL20541378 | 0.84 | KLKB1 (0.45) | KLKB1POLB | |
| SCHEMBL30140745 | 0.84 | KLKB1 (0.45) | KLKB1POLB | |
| SCHEMBL21736734 | 0.83 | KLKB1 (0.41) | KLKB1POLBMAPTGRM2PIK3CD | |
| SCHEMBL23769156 | 0.81 | KLKB1 (0.51) | KLKB1GRM2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039181-B | Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein | 勃林格殷格翰国际有限公司 | 2024-08-13 | — | — | CN | disclosed |