Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 2/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31033251 | 0.84 | RAB9A (0.52) | MEN1KMT2ARAB9APOLBNPC1 | |
| SCHEMBL31033248 | 0.81 | MAOA (0.58) | PIK3CGMEN1KMT2ARAB9APOLB | |
| SCHEMBL31033247 | 0.74 | MAOA (0.43) | PIK3CGMEN1KMT2ARAB9APOLB | |
| SCHEMBL28427466 | 0.71 | MAPT (0.68) | PIK3CGMEN1KMT2ARAB9APOLB | |
| SCHEMBL1636725 | 0.68 | SRC (0.47) | PIK3CGMEN1KMT2ARAB9APOLB | |
| SCHEMBL4360909 | 0.68 | APP (0.45) | MEN1KMT2ARAB9APOLBNPC1 | |
| SCHEMBL31033250 | 0.66 | MAOA (0.58) | MEN1KMT2ARAB9APOLBNPC1 | |
| SCHEMBL9896463 | 0.66 | PIK3CG (1.00) | PIK3CGMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL31033260 | 0.64 | RAB9A (0.49) | MEN1KMT2ARAB9APOLBNPC1 | |
| SCHEMBL14243596 | 0.64 | APP (0.68) | PIK3CGMEN1KMT2ARAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118420557-B | Zhu Gongjun acid analogue, and preparation method and application thereof | 济南爱思医药科技有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-118420557-A | Zhu Gongjun acid analogue, and preparation method and application thereof | 济南爱思医药科技有限公司 | 2024-08-02 | — | — | CN | disclosed |