Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19344901 | 0.79 | ADRA2A (0.30) | ADRA2AADRA2BADRA2CADRA1B | |
| Atipamezole SCHEMBL881064 | 0.71 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CADRA1BKMT2A | |
| Atipamezole SCHEMBL3526769 | 0.70 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CADRA1BKMT2A | |
| Atipamezole SCHEMBL31147780 | 0.70 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CADRA1BKMT2A | |
| SCHEMBL31034929 | 0.69 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CADRA1BKMT2A | |
| SCHEMBL31683939 | 0.68 | CYP2D6 (0.58) | ADRA2AADRA2BADRA2CADRA1BKMT2A | |
| Atipamezole SCHEMBL29357620 | 0.68 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1B | |
| Atipamezole SCHEMBL304971 | 0.68 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1B | |
| Atipamezole SCHEMBL203964 | 0.67 | ADRA2A (0.97) | ADRA2AADRA2BADRA2CADRA1BKMT2A | |
| Atipamezole SCHEMBL30249868 | 0.67 | ADRA2A (0.97) | ADRA2AADRA2BADRA2CADRA1BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658639-A1 | N,N-DIALKYL-4-(2-ETHYLINDAN-2-YL)-1H-IMIDAZOLE-1-CARBOXAMIDES AND RELATED COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISEASES | Univerza V Ljubljani (SI) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024160908-A1 | N,N-DIALKYL-4-(2-ETHYLINDAN-2-YL)-1H-IMIDAZOLE-1-CARBOXAMIDES AND RELATED COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISEASES | UNIVERZA V LJUBLJANI (SI) | 2024-08-08 | — | — | WO | disclosed |