Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29714630 | 1.00 | HCRTR2 (0.46) | HCRTR2GPR119 | |
| SCHEMBL29714613 | 0.86 | HCRTR2 (0.49) | HCRTR2GPR119 | |
| SCHEMBL29714602 | 0.86 | HCRTR2 (0.49) | HCRTR2GPR119 | |
| SCHEMBL29714609 | 0.84 | GPR119 (0.40) | HCRTR2GPR119 | |
| SCHEMBL31035130 | 0.83 | HCRTR2 (0.53) | HCRTR2 | |
| SCHEMBL24589448 | 0.76 | GPR119 (0.38) | HCRTR2GPR119 | |
| SCHEMBL30487910 | 0.75 | PTGDR2 (0.38) | HCRTR2GPR119 | |
| SCHEMBL31035005 | 0.74 | HCRTR2 (0.42) | HCRTR2GPR119 | |
| SCHEMBL31034872 | 0.72 | HCRTR2 (0.45) | HCRTR2GPR119 | |
| SCHEMBL31757393 | 0.72 | HCRTR2 (0.72) | HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658660-A1 | MACROCYCLIC OREXIN RECEPTOR AGONISTS AND USES THEREOF | Jazz Pharmaceuticals Ireland Limited (IE) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024160822-A1 | MACROCYCLIC OREXIN RECEPTOR AGONISTS AND USES THEREOF | JAZZ PHARMACEUTICALS IRELAND LIMITED (IE) | 2024-08-08 | — | — | WO | disclosed |