Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23925544 | 0.74 | PDE4B (0.34) | GAA | |
| SCHEMBL25344154 | 0.72 | CDK5 (0.31) | CDK5CDK5R1 | |
| SCHEMBL25347234 | 0.68 | PDE3A (0.33) | CDK5CDK5R1 | |
| SCHEMBL23950469 | 0.66 | PDE4B (0.38) | GAA | |
| SCHEMBL23950161 | 0.66 | PDE4B (0.40) | GAA | |
| SCHEMBL31684809 | 0.65 | TP53 (0.54) | CDK5CDK5R1 | |
| SCHEMBL23925370 | 0.64 | PARP1 (0.39) | — | |
| SCHEMBL4194913 | 0.64 | PIK3CA (0.36) | CDK5CDK5R1 | |
| SCHEMBL31521324 | 0.63 | PDE10A (0.34) | CDK5CDK5R1 | |
| SCHEMBL16317806 | 0.62 | PARP1 (0.51) | CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658654-A1 | PYRROLO[1,2-D][1,2,4]TRIAZINES AND PYRAZOLO[1,5-D] [1,2,4]TRIAZINES AS NLRP3 INHIBITORS | Janssen Pharmaceutica NV (BE) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024160691-A1 | PYRROLO[1,2-d][1,2,4]TRIAZINES AND PYRAZOLO[1,5-d] [1,2,4]TRIAZINES AS NLRP3 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-08-08 | — | — | WO | disclosed |