Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 11/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31035016 | 0.85 | PIK3CA (0.34) | PIK3CAAKT1AKT2AKT3GPR55 | |
| SCHEMBL31035774 | 0.81 | AKT1 (0.37) | PIK3CAAKT1AKT2AKT3KDM4E | |
| SCHEMBL31035594 | 0.79 | ESR2 (0.39) | ESR1ESR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL31035338 | 0.78 | KDM4E (0.35) | PIK3CAAKT1AKT2AKT3KDM4E | |
| SCHEMBL31035499 | 0.78 | PIK3CA (0.38) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL30889677 | 0.78 | PIK3CA (0.38) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL24912998 | 0.77 | ALDH1A1 (0.49) | PIK3CAAKT1AKT2AKT3KDM4E | |
| SCHEMBL31035409 | 0.77 | ALDH1A1 (0.49) | PIK3CAAKT1AKT2AKT3KDM4E | |
| SCHEMBL30893165 | 0.77 | ALDH1A1 (0.49) | PIK3CAAKT1AKT2AKT3KDM4E | |
| SCHEMBL23887394 | 0.77 | PIK3CA (0.34) | PIK3CAAKT1AKT2AKT3CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680612-A1 | CHEMICAL COMPOUNDS | AN2 Therapeutics, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024192309-A1 | CHEMICAL COMPOUNDS | REACTIVE BIOSCIENCES, INC. (US) | 2024-09-19 | — | — | WO | disclosed |