Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31035313 | 0.78 | KDM4E (0.36) | KDM4EMAPTHSD17B10ALDH1A1NPC1 | |
| SCHEMBL31035274 | 0.78 | PIK3CA (0.36) | KDM4EHSD17B10PIK3CAAKT1AKT2 | |
| SCHEMBL31035594 | 0.78 | ESR2 (0.39) | MAOBESR1ESR2CSNK2A2CSNK2B | |
| SCHEMBL31035016 | 0.75 | PIK3CA (0.34) | PIK3CAAKT1AKT2AKT3 | |
| SCHEMBL31035222 | 0.75 | KDM4E (0.34) | KDM4EMAPTHSD17B10ALDH1A1NPC1 | |
| SCHEMBL23887184 | 0.74 | KDM4E (0.33) | KDM4EMAPTHSD17B10ALDH1A1NPC1 | |
| SCHEMBL24912981 | 0.74 | ALDH1A1 (0.50) | KDM4EMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL31035139 | 0.72 | AKT1 (0.46) | ALDH1A1NPC1SMN1; SMN2PIK3CAAKT1 | |
| SCHEMBL31035046 | 0.72 | KDM4E (0.32) | KDM4EMAPTHSD17B10ALDH1A1NPC1 | |
| SCHEMBL25181499 | 0.71 | PIK3CA (0.34) | KDM4EMAPTHSD17B10ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680612-A1 | CHEMICAL COMPOUNDS | AN2 Therapeutics, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024192309-A1 | CHEMICAL COMPOUNDS | REACTIVE BIOSCIENCES, INC. (US) | 2024-09-19 | — | — | WO | disclosed |