Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 4/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31035338 | 0.78 | KDM4E (0.35) | KDM4EHSD17B10NPC1ALDH1A1MAPT | |
| SCHEMBL31035336 | 0.77 | ESR1 (0.40) | ALDH1A1MAPTCDK2ESR1ESR2 | |
| SCHEMBL31035222 | 0.76 | KDM4E (0.34) | KDM4EHSD17B10NPC1ALDH1A1MAPT | |
| SCHEMBL31035774 | 0.75 | AKT1 (0.37) | KDM4EHSD17B10AKT1AKT2AKT3 | |
| SCHEMBL24912981 | 0.75 | ALDH1A1 (0.50) | KDM4ENPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL23887184 | 0.75 | KDM4E (0.33) | KDM4EHSD17B10NPC1ALDH1A1MAPT | |
| SCHEMBL23887230 | 0.74 | AKT1 (0.56) | AKT1AKT2AKT3PIK3CA | |
| SCHEMBL31035207 | 0.74 | PIK3CA (0.51) | AKT1AKT2AKT3PIK3CA | |
| SCHEMBL31035139 | 0.73 | AKT1 (0.46) | NPC1ALDH1A1SMN1; SMN2TSHRAKT1 | |
| SCHEMBL31035046 | 0.73 | KDM4E (0.32) | KDM4EHSD17B10NPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680612-A1 | CHEMICAL COMPOUNDS | AN2 Therapeutics, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024192309-A1 | CHEMICAL COMPOUNDS | REACTIVE BIOSCIENCES, INC. (US) | 2024-09-19 | — | — | WO | disclosed |