SCHEMBL3103532

SCHEMBL3103532

COc1nc(C)nc(CNC(=O)NS(=O)(=O)C2(C)C=CC=CC2C(=O)O)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10506669 0.85 GAA (0.35)
SCHEMBL5262913 0.85
SCHEMBL3304539 0.84 GAA (0.33)
SCHEMBL8763376 0.80
SCHEMBL9394284 0.74 MAPT (0.36)
SCHEMBL11094712 0.73
SCHEMBL6313348 0.73 GAA (0.48)
SCHEMBL10805642 0.72 ALDH1A1 (0.31)
SCHEMBL11073812 0.71 GAA (0.38)
SCHEMBL9055607 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0496608-B1 Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same ISHIHARA SANGYO KAISHA (JP) 1995-09-20 EP claimed
US-20150344902-A1 Resistance to Acetohydroxyacid Synthase-Inhibiting Herbicides BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2015-12-03 US disclosed
US-20150216126-A1 Herbicide Resistant Rice BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2015-08-06 US disclosed
US-9090904-B2 Resistance to acetohydroxyacid synthase-inhibiting herbicides BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2015-07-28 US disclosed
EP-2882293-A1 HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID Dow AgroSciences LLC (US) 2015-06-17 EP disclosed
US-9029642-B2 Herbicide resistant rice BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2015-05-12 US disclosed
WO-2014018410-A1 HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID DOW AGROSCIENCES LLC (US) 2014-01-30 WO disclosed
US-20100257623-A1 Herbicide Resistant Rice CROUGHAN TIMOTHY P 2010-10-07 US disclosed
US-7399905-B2 Resistance to acetohydroxyacid synthase-inhibiting herbicides in rice BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2008-07-15 US disclosed
US-7019196-B1 resistant to acetohydroxyacid synthase (AHAS) enzyme inhibitors such as imnazethapyr, imazapyr, nicosulfuron, imazaquin, imazamox, metsulfuron methyl, thifensulfuron methyl, tribenuron methyl, and pyrithiobac sodium BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2006-03-28 US disclosed
US-6943280-B2 Resistance to acetohydroxycid synthase-inhibiting herbicides BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2005-09-13 US disclosed
US-20050198705-A1 Resistance to acetohydroxyacid synthase-inhibiting herbicides CROUGHAN TIMOTHY P (US) 2005-09-08 US disclosed
EP-1194037-B1 AGROCHEMICAL COMPOSITIONS AND SURFACTANT COMPOUNDS ICI PLC (GB) 2004-08-18 EP disclosed
US-20030217381-A1 Resistance to acetohydroxycid synthase-inhibiting herbicides BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE 2003-11-20 US disclosed
EP-1168916-B1 AGROCHEMICAL FORMULATIONS ICI PLC (GB) 2003-09-17 EP disclosed
EP-0524482-B1 Substituted triazoles and their use as herbicides BAYER AG (DE) 1994-06-08 EP disclosed
US-5198599-A Sulfonylurea herbicide resistance in plants IDAHO RESARCH FOUNDATION, INC. (US) 1993-03-30 US disclosed
EP-0524482-A1 Substituted triazoles and their use as herbicides BAYER AG (DE) 1993-01-27 EP disclosed