SCHEMBL3304539

SCHEMBL3304539

COc1nc(C)nc(NC(=O)NS(=O)(=O)C2(C)C=CC=CC2C(=O)O)n1

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.33
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9394284 0.88 MAPT (0.36) GAA
SCHEMBL11094712 0.88
SCHEMBL6313348 0.85 GAA (0.48) GAAALOX15
SCHEMBL3103532 0.84
SCHEMBL11072808 0.83 GAA (0.31) GAAALOX15
SCHEMBL4047513 0.83 GAA (0.43) GAAALOX15
SCHEMBL11073812 0.83 GAA (0.38) GAA
Sulfometuron Methyl SCHEMBL9755752 0.83 NPC1 (0.33) GAAALOX15
SCHEMBL11072278 0.82 GAA (0.31) GAA
SCHEMBL11071268 0.81 GAA (0.30) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0901753-B1 HERBICIDAL COMPOSITION UBE INDUSTRIES (JP) 2004-04-28 EP claimed
EP-0575489-B1 WATER-DISPERSIBLE GRANULAR AGRICULTURAL COMPOSITIONS MADE BY HEAT EXTRUSION DU PONT (US) 1997-07-02 EP claimed
EP-0637909-B1 REVERSIBLE AGRICULTURAL GEL AND PASTE FORMULATIONS DU PONT (US) 1997-02-26 EP claimed
EP-0496608-B1 Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same ISHIHARA SANGYO KAISHA (JP) 1995-09-20 EP claimed
US-5441923-A Water-soluble or water dispersible pesticide granules comprising sulfonylurea herbicides in a polyethylene or polypropylene coating E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-08-15 US claimed
EP-0471284-B1 Herbicidal compositions IDEMITSU KOSAN CO (JP) 1995-01-18 EP claimed
EP-0422026-B1 TABLET FORMULATIONS OF PESTICIDES DU PONT (US) 1994-09-07 EP claimed
EP-0360441-B1 Water-soluble or water-dispersible pesticide granules DU PONT (US) 1994-04-27 EP claimed
EP-0298901-B1 HERBICIDAL AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1992-01-15 EP claimed
EP-0360441-A1 Water-soluble or water-dispersible pesticide granules E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-28 EP claimed
US-4818278-A N-/HETEROCYCLICAMINOCARBONYL/ARYL SULFONAMIDES; HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-04-04 US claimed
JP-1034903-A None JP disclosed
EP-2882293-A1 HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID Dow AgroSciences LLC (US) 2015-06-17 EP disclosed
WO-2014018410-A1 HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID DOW AGROSCIENCES LLC (US) 2014-01-30 WO disclosed
US-20100099562-A1 HERBICIDE COMBINATION BAYER CROPSCIENCE AG (DE) 2010-04-22 US disclosed
WO-1990006308-A1 PROCESS FOR PREPARING SULFONYLUREA SALTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-06-14 WO disclosed
WO-1990002486-A1 WATER-SOLUBLE OR WATER-DISPERSIBLE PESTICIDE GRANULES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-22 WO disclosed
JP-S6434903-A HERBICIDE HOECHST AG 1989-02-06 JP disclosed
EP-0298901-A2 Herbicidal agents HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-11 EP disclosed
JP-S06434903-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099562-A1 HERBICIDE COMBINATION DDT, MSRB3, PTPN21 GAA 1224/4885ALOX15 3688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.