Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23727661 | 0.86 | KDM4E (0.47) | KDM4EPOLBCYP1A2GAARAB9A | |
| SCHEMBL21033151 | 0.85 | KDM4E (0.48) | KDM4EPOLBGAAMAPK1RAB9A | |
| SCHEMBL23728535 | 0.80 | APOBEC3A (0.53) | KDM4EPOLBGAARAB9ANPC1 | |
| SCHEMBL4794765 | 0.77 | APOBEC3A (0.61) | KDM4EPOLBCYP1A2GAARAB9A | |
| SCHEMBL3561838 | 0.76 | MAPT (0.55) | KDM4EPOLBCYP1A2GAAMAPK1 | |
| SCHEMBL30896072 | 0.74 | DRD2 (0.47) | KDM4EPOLBCYP1A2GAAKMT2A | |
| SCHEMBL18343709 | 0.74 | KDM4E (0.47) | KDM4EPOLBCYP1A2GAARAB9A | |
| SCHEMBL25887632 | 0.73 | MAPT (0.48) | KDM4EPOLBCYP1A2GAAALDH1A1 | |
| SCHEMBL18343707 | 0.73 | KDM4E (0.46) | KDM4EPOLBCYP1A2GAAMAPK1 | |
| SCHEMBL21192982 | 0.72 | CYP1A2 (0.45) | KDM4EPOLBCYP1A2GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118434744-A | Nitrogen-containing macrocyclic compound, and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2024-08-02 | — | — | CN | disclosed |