Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.45 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29263660 | 1.00 | HDAC1 (0.59) | HDAC1HDAC8RELAPTGS1CNR2 | |
| SCHEMBL7172671 | 0.93 | HDAC1 (0.64) | HDAC1HDAC8RELAPTGS1CNR2 | |
| SCHEMBL10743046 | 0.89 | RELA (0.55) | HDAC1HDAC8RELAPTGS1CNR2 | |
| SCHEMBL10743059 | 0.89 | RELA (0.55) | HDAC1HDAC8RELAPTGS1CNR2 | |
| SCHEMBL29084182 | 0.83 | HDAC1 (0.56) | HDAC1HDAC8RELAPTGS1GRIK1 | |
| SCHEMBL9819809 | 0.83 | HDAC1 (0.56) | HDAC1HDAC8RELAPTGS1CNR2 | |
| SCHEMBL9819805 | 0.83 | HDAC1 (0.56) | HDAC1HDAC8RELAPTGS1CNR2 | |
| SCHEMBL29084177 | 0.83 | HDAC1 (0.56) | HDAC1HDAC8RELAPTGS1GRIK1 | |
| SCHEMBL3973218 | 0.82 | RELA (0.59) | HDAC1HDAC8RELAPTGS1CNR2 | |
| SCHEMBL6500171 | 0.82 | RELA (0.59) | HDAC1HDAC8RELAPTGS1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255685-A | Tricyclic compound, pharmaceutical composition and application thereof | 珂阑(上海)医药科技有限公司 | 2024-06-28 | — | — | CN | disclosed |