Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.49 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6500171 | 1.00 | RELA (0.59) | RELAPTGS1ALDH1A1CYP3A4RECQL | |
| SCHEMBL11351372 | 0.94 | ALDH1A1 (0.53) | RELAPTGS1ALDH1A1CYP3A4RECQL | |
| SCHEMBL8648985 | 0.92 | ALDH1A1 (0.63) | RELAPTGS1ALDH1A1CYP3A4RECQL | |
| SCHEMBL8648982 | 0.92 | ALDH1A1 (0.63) | RELAPTGS1ALDH1A1CYP3A4RECQL | |
| SCHEMBL10746611 | 0.87 | CNR2 (0.55) | RELAPTGS1ALDH1A1CYP3A4HDAC1 | |
| SCHEMBL10746614 | 0.87 | CNR2 (0.55) | RELAPTGS1ALDH1A1CYP3A4HDAC1 | |
| SCHEMBL10743059 | 0.85 | RELA (0.55) | RELAPTGS1ALDH1A1HDAC1KDM4E | |
| SCHEMBL10743046 | 0.85 | RELA (0.55) | RELAPTGS1ALDH1A1HDAC1KDM4E | |
| SCHEMBL31035992 | 0.82 | HDAC1 (0.59) | RELAPTGS1ALDH1A1CYP3A4HDAC1 | |
| SCHEMBL29263660 | 0.82 | HDAC1 (0.59) | RELAPTGS1ALDH1A1CYP3A4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10112896-B2 | Method for synthesizing dissymmetric sulfoether | SOOCHOW UNIVERSITY (CN) | 2018-10-30 | — | — | US | claimed |
| US-20180201576-A1 | METHOD FOR SYNTHESIZING DISSYMMETRIC SULFOETHER | SOOCHOW UNIVERSITY (CN) | 2018-07-19 | — | — | US | claimed |
| CN-113429249-B | Method for synthesizing chiral 4-hydroxy amino acid derivative | 陕西师范大学 | 2023-06-16 | — | — | CN | disclosed |
| CN-111320591-B | Method for synthesizing chiral gamma-amino alcohol | 陕西师范大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-113429249-A | Method for synthesizing chiral 4-hydroxy amino acid derivative | 陕西师范大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-111320591-A | Method for synthesizing chiral gamma-amino alcohol | 陕西师范大学 | 2020-06-23 | — | — | CN | disclosed |
| US-10112896-B2 | Method for synthesizing dissymmetric sulfoether | SOOCHOW UNIVERSITY (CN) | 2018-10-30 | — | — | US | disclosed |
| US-20180201576-A1 | METHOD FOR SYNTHESIZING DISSYMMETRIC SULFOETHER | SOOCHOW UNIVERSITY (CN) | 2018-07-19 | — | — | US | disclosed |
| US-20150290200-A1 | INTRACELLULAR KINASE INHIBITORS | PHARMACYCLICS INC (US) | 2015-10-15 | — | — | US | disclosed |
| WO-2009051661-A2 | SUBSTITUTED ARYL ALKYLAMINO-OXY-ANALOGS AND USES THEREOF | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2009-04-23 | — | — | WO | disclosed |
| EP-2027087-A2 | INTRACELLULAR KINASE INHIBITORS | MannKind Corporation (US) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007136790-A2 | INTRACELLULAR KINASE INHIBITORS | MANNKIND CORPORATION (US) | 2007-11-29 | — | — | WO | disclosed |
| US-6867218-B2 | Compounds, their preparation and use | NOVO NORDISK A/S (DK) | 2005-03-15 | — | — | US | disclosed |
| US-20030195200-A1 | Compounds, their preparation and use | VTVX HOLDINGS II LLC | 2003-10-16 | — | — | US | disclosed |
| US-6555577-B1 | For treatment and/or prevention of conditions mediated by the Peroxisome Proliferator-Activated Receptors (PPAR), such as diabetes and/or obesity; 3-(4-(3-Biphenyl-4-yl-but-2-enyloxy)-phenyl)-2-butoxy-propionic acid for example | NOVO NORDISK A/S (DE) | 2003-04-29 | — | — | US | disclosed |
| EP-0974584-B1 | FUSED RING COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-01-15 | — | — | EP | disclosed |
| US-6420375-B1 | ANTITUMOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| WO-2002017973-A2 | PREPARING STERILE ARTICLES FROM CERTAIN POLYMERS | OCCIDENTAL CHEMICAL CORPORATION (US) | 2002-03-07 | — | — | WO | disclosed |
| EP-0974584-A1 | FUSED RING COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-01-26 | — | — | EP | disclosed |
| US-3995054-A | MITICIDES | ZOECON CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10112896-B2 | Method for synthesizing dissymmetric sulfoether | STS, TST, SCLY | RELA 1685/4885PTGS1 1501/4885ALDH1A1 842/4885 |
| US-20180201576-A1 | METHOD FOR SYNTHESIZING DISSYMMETRIC SULFOETHER | STS, TST, SCLY | RELA 1685/4885PTGS1 1501/4885ALDH1A1 842/4885 |
| US-20150290200-A1 | INTRACELLULAR KINASE INHIBITORS | PI4KB, BTK, LTK | RELA 2101/4885PTGS1 3298/4885ALDH1A1 4370/4885 |
| US-20030195200-A1 | Compounds, their preparation and use | PPARG, PPARA, PPARD | RELA 676/4885PTGS1 142/4885ALDH1A1 257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.