Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 10/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 9/20 | 0.39 |
| ▸ | RXRA | P19793 | 8/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24451644 | 0.88 | IP6K1 (0.40) | NR1H2NR1H3RXRAKMT2A | |
| SCHEMBL29616596 | 0.88 | NR1H2 (0.39) | NR1H2NR1H3RXRACYP1A2CYP2C19 | |
| SCHEMBL30917881 | 0.88 | NR1H2 (0.39) | NR1H2NR1H3RXRACYP1A2CYP2C19 | |
| SCHEMBL24454023 | 0.88 | IP6K1 (0.40) | NR1H2NR1H3RXRAKMT2A | |
| SCHEMBL27034795 | 0.88 | NR1H2 (0.39) | NR1H2NR1H3RXRACYP1A2CYP2C19 | |
| SCHEMBL24403239 | 0.86 | NR1H2 (0.48) | NR1H2NR1H3RXRA | |
| SCHEMBL24403238 | 0.86 | NR1H2 (0.48) | NR1H2NR1H3RXRA | |
| SCHEMBL30599282 | 0.86 | NR1H2 (0.48) | NR1H2NR1H3RXRA | |
| SCHEMBL30599281 | 0.86 | NR1H2 (0.48) | NR1H2NR1H3RXRA | |
| SCHEMBL24380232 | 0.86 | NR1H2 (0.38) | NR1H2NR1H3RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118165071-A | Oxo-spiro indoline compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-06-11 | — | — | CN | disclosed |