Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 9/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31037087 | 0.87 | POLB (0.40) | KHKNPC1RAB9APAX8SPR | |
| SCHEMBL31037105 | 0.87 | NPC1 (0.44) | KHKNPC1RAB9APAX8MPO | |
| SCHEMBL31037097 | 0.86 | KHK (0.43) | KHKNPC1RAB9APAX8ALDH1A1 | |
| SCHEMBL31037089 | 0.85 | KHK (0.42) | KHKNPC1RAB9APAX8MPO | |
| SCHEMBL25301915 | 0.83 | SPR (0.49) | KHKSPRALDH1A1 | |
| SCHEMBL31037064 | 0.80 | CA9 (0.45) | KHKNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL31037068 | 0.77 | CYP11B1 (0.41) | KHKRAB9AMAPTCYP11B1CYP11B2 | |
| SCHEMBL28719142 | 0.77 | CYP11B1 (0.41) | KHKRAB9AMAPTCYP11B1CYP11B2 | |
| SCHEMBL31037073 | 0.75 | POLB (0.46) | KHKALDH1A1MAPT | |
| SCHEMBL31037079 | 0.74 | ATM (0.48) | KHKNPC1RAB9APAX8MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454068-B | Benzonazolone compounds and intermediates thereof | LMITO药业株式会社 | 2024-08-02 | — | — | CN | disclosed |