Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 2/20 | 0.41 |
| ▸ | KHK | P50053 | 2/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28719142 | 1.00 | CYP11B1 (0.41) | CYP11B1CYP11B2CASRKHKMAT2A | |
| SCHEMBL31037099 | 0.86 | CASR (0.42) | CYP11B1CYP11B2CASRKHKMAT2A | |
| SCHEMBL28715241 | 0.86 | CASR (0.42) | CYP11B1CYP11B2CASRKHKMAT2A | |
| SCHEMBL31037087 | 0.86 | POLB (0.40) | CYP11B1CYP11B2KHKRAB9APOLB | |
| SCHEMBL31037105 | 0.86 | NPC1 (0.44) | CYP11B1CYP11B2KHKRAB9AKDM4E | |
| SCHEMBL31037098 | 0.77 | KHK (0.42) | CYP11B1CYP11B2KHKMAPTRAB9A | |
| SCHEMBL31037089 | 0.74 | KHK (0.42) | CYP11B1CYP11B2KHKRAB9A | |
| SCHEMBL25258035 | 0.73 | CYP11B2 (0.43) | CYP11B1CYP11B2MAPTNPSR1POLB | |
| SCHEMBL29402177 | 0.73 | CYP11B2 (0.43) | CYP11B1CYP11B2MAPTNPSR1POLB | |
| SCHEMBL31037061 | 0.72 | MAPT (0.41) | MAPTL3MBTL1KDM4EPOLBALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454068-B | Benzonazolone compounds and intermediates thereof | LMITO药业株式会社 | 2024-08-02 | — | — | CN | disclosed |