Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13151350 | 1.00 | CXCR3 (0.84) | CXCR3CYP3A4 | |
| SCHEMBL27015149 | 0.91 | CXCR3 (0.87) | CXCR3CYP3A4 | |
| SCHEMBL3097262 | 0.90 | CXCR3 (0.84) | CXCR3CYP3A4 | |
| SCHEMBL13151363 | 0.90 | CXCR3 (0.77) | CXCR3CYP3A4 | |
| SCHEMBL3097273 | 0.90 | CXCR3 (0.84) | CXCR3CYP3A4 | |
| SCHEMBL13151352 | 0.89 | CXCR3 (0.68) | CXCR3CYP3A4 | |
| SCHEMBL13151349 | 0.88 | CXCR3 (0.66) | CXCR3CYP3A4 | |
| SCHEMBL3097340 | 0.88 | CXCR3 (0.66) | CXCR3CYP3A4 | |
| SCHEMBL3098066 | 0.88 | CXCR3 (0.66) | CXCR3CYP3A4 | |
| SCHEMBL10087500 | 0.85 | CXCR3 (0.97) | CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799795-B2 | Aryl nitrile compounds and compositions and their uses in treating inflammatory and related disorders | AMGEN INC. (US) | 2010-09-21 | — | — | US | claimed |