SCHEMBL27015149

SCHEMBL27015149

CCOc1ccc(-n2c(C(C)N(Cc3cccnc3)C(=O)Cc3ccc(C(F)(F)F)cc3)nc3ncccc3c2=O)cc1

nearest known ligand 0.87

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CXCR3 P49682 20/20 0.87
CYP3A4 P08684 2/20 0.87

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29386766 0.93 CXCR3 (1.00) CXCR3CYP3A4
SCHEMBL335753 0.93 CXCR3 (1.00) CXCR3CYP3A4
SCHEMBL433439 0.93 CXCR3 (1.00) CXCR3CYP3A4
SCHEMBL5838280 0.92 CXCR3 (1.00) CXCR3
Hydrochloric Acid SCHEMBL5833406 0.92 CXCR3 (0.99) CXCR3
SCHEMBL14960668 0.91 CXCR3 (1.00) CXCR3CYP3A4
SCHEMBL13151350 0.91 CXCR3 (0.84) CXCR3CYP3A4
SCHEMBL3103733 0.91 CXCR3 (0.84) CXCR3CYP3A4
SCHEMBL29411739 0.90 CXCR3 (1.00) CXCR3CYP3A4
SCHEMBL22965110 0.90 CXCR3 (1.00) CXCR3CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240016813-A1 METHODS OF TREATING SYMPTOMS OF CORONAVIRUS INFECTION Accencio LLC 2024-01-18 US disclosed
US-20240016813-A1 METHODS OF TREATING SYMPTOMS OF CORONAVIRUS INFECTION Accencio LLC 2024-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240016813-A1 METHODS OF TREATING SYMPTOMS OF CORONAVIRUS INFECTION ACE2, ACE, TMPRSS2 CXCR3 963/4885CYP3A4 1847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.