Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | ACACA | Q13085 | 2/20 | 0.43 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31037658 | 0.92 | KDM4E (0.45) | KDM4EPKMBRD4TGFBR1ACACB | |
| SCHEMBL6837831 | 0.81 | KDM4E (0.44) | KDM4EPKMGPR119HTR6 | |
| SCHEMBL27213594 | 0.80 | MET (0.46) | KDM4E | |
| SCHEMBL6923708 | 0.78 | KDM4E (0.48) | KDM4EPKMBRD4TGFBR1ACACB | |
| SCHEMBL213119 | 0.77 | KCNH3 (0.42) | KDM4EPKMHTR6CYP2D6CYP2C9 | |
| SCHEMBL13793840 | 0.77 | KDM4E (0.58) | KDM4EPKMBRD4PRMT5TGFBR1 | |
| SCHEMBL843596 | 0.76 | BCHE (0.49) | BRD4ACACBACACA | |
| SCHEMBL3863551 | 0.76 | KDM4E (0.47) | KDM4EPKMBRD4PRMT5TGFBR1 | |
| SCHEMBL29381474 | 0.75 | EGFR (0.55) | PKMBRD4ACACBACACA | |
| SCHEMBL212541 | 0.75 | EGFR (0.55) | PKMBRD4ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024138157-A1 | NOVEL IMIDAZOQUINOLINES WITH IMMUNOSTIMULATORY EFFECTS | SYNOVO GMBH (DE) | 2024-06-27 | — | — | WO | disclosed |