Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 16/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31037806 | 0.92 | DHPS (0.80) | DHPSALDH1A1 | |
| SCHEMBL31037832 | 0.89 | DHPS (0.65) | DHPSALDH1A1HTR1AADRA1DADRA1A | |
| SCHEMBL7850977 | 0.89 | DHPS (0.65) | DHPS | |
| SCHEMBL31037801 | 0.88 | DHPS (0.82) | DHPSMAPT | |
| SCHEMBL31037828 | 0.88 | DHPS (0.63) | DHPSMAPT | |
| SCHEMBL31037812 | 0.88 | DHPS (0.63) | DHPS | |
| SCHEMBL31037842 | 0.85 | DHPS (0.70) | DHPSALDH1A1MAPT | |
| SCHEMBL31037848 | 0.85 | DHPS (0.70) | DHPSALDH1A1MAPT | |
| SCHEMBL31037814 | 0.82 | DHPS (0.69) | DHPSALDH1A1MAPT | |
| SCHEMBL31037836 | 0.82 | DHPS (0.69) | DHPSMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118666758-A | Anti-melanoma benzyl pyrimidine compound and preparation method and application thereof | 中国医科大学附属盛京医院 | 2024-09-20 | — | — | CN | claimed |
| CN-118666758-A | Anti-melanoma benzyl pyrimidine compound and preparation method and application thereof | 中国医科大学附属盛京医院 | 2024-09-20 | — | — | CN | disclosed |