Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 13/20 | 0.69 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31037819 | 0.91 | DHPS (0.84) | DHPSALDH1A1NPSR1 | |
| SCHEMBL31037848 | 0.90 | DHPS (0.70) | DHPSALDH1A1MAPTTSHRLMNA | |
| SCHEMBL31037842 | 0.90 | DHPS (0.70) | DHPSALDH1A1MAPTTSHRLMNA | |
| SCHEMBL31037801 | 0.90 | DHPS (0.82) | DHPSMAPTTSHRMAPK1L3MBTL1 | |
| SCHEMBL31037805 | 0.89 | DHPS (0.69) | DHPSMAPTTSHRMAPK1L3MBTL1 | |
| SCHEMBL31037836 | 0.89 | DHPS (0.69) | DHPSMAPTTSHRMAPK1L3MBTL1 | |
| SCHEMBL31037821 | 0.88 | DHPS (0.67) | DHPSALDH1A1MAPTTSHRMAPK1 | |
| SCHEMBL7850977 | 0.86 | DHPS (0.65) | DHPSTSHRLMNAHTT | |
| SCHEMBL31037825 | 0.82 | DHPS (0.62) | DHPSALDH1A1L3MBTL1 | |
| SCHEMBL31037804 | 0.82 | DHPS (0.66) | DHPSALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118666758-A | Anti-melanoma benzyl pyrimidine compound and preparation method and application thereof | 中国医科大学附属盛京医院 | 2024-09-20 | — | — | CN | claimed |
| CN-118666758-A | Anti-melanoma benzyl pyrimidine compound and preparation method and application thereof | 中国医科大学附属盛京医院 | 2024-09-20 | — | — | CN | disclosed |