Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 10/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTR1F | P30939 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30842129 | 0.88 | KIF18A (0.48) | KIF18A | |
| SCHEMBL31037907 | 0.85 | KIF18A (0.49) | KIF18A | |
| SCHEMBL31037905 | 0.85 | KIF18A (0.49) | KIF18A | |
| SCHEMBL31037917 | 0.83 | BACE1 (0.36) | KIF18AMAPTGSK3AALDH1A1SMN1; SMN2 | |
| SCHEMBL31037925 | 0.83 | BACE1 (0.36) | KIF18AMAPTGSK3AALDH1A1SMN1; SMN2 | |
| SCHEMBL31037918 | 0.79 | KIF18A (0.37) | KIF18AMAPTALDH1A1 | |
| SCHEMBL31037921 | 0.78 | TP53 (0.36) | KIF18AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL31037924 | 0.77 | KIF18A (0.39) | KIF18AGSK3A | |
| SCHEMBL31546241 | 0.76 | KIF18A (0.43) | KIF18A | |
| SCHEMBL30842134 | 0.73 | KIF18A (0.61) | KIF18A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118666851-A | Condensed ring KIF18A inhibitor compound, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-09-20 | — | — | CN | disclosed |