Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 20/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30842129 | 0.88 | KIF18A (0.48) | KIF18A | |
| SCHEMBL30842167 | 0.84 | KIF18A (0.63) | KIF18A | |
| SCHEMBL31037919 | 0.76 | KIF18A (0.36) | KIF18A | |
| SCHEMBL31613814 | 0.75 | KIF18A (0.59) | KIF18A | |
| SCHEMBL30842127 | 0.74 | KIF18A (0.49) | KIF18A | |
| SCHEMBL30842134 | 0.73 | KIF18A (0.61) | KIF18A | |
| SCHEMBL31613844 | 0.73 | KIF18A (0.61) | KIF18A | |
| SCHEMBL31613840 | 0.73 | KIF18A (0.61) | KIF18A | |
| SCHEMBL30856607 | 0.73 | KIF18A (0.45) | KIF18A | |
| SCHEMBL30842186 | 0.72 | TGFBR1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4567032-A1 | KIF18A INHIBITOR COMPOUND, AND PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR AND USE THEREOF | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2025-06-11 | — | — | EP | disclosed |
| CN-119731163-A | KIF18A inhibitor compound, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2025-03-28 | — | — | CN | disclosed |