Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GOT1 | P17174 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4093611 | 1.00 | NAMPT (0.46) | NAMPTFFAR2METAP1CYP17A1RAB9A | |
| SCHEMBL9370108 | 0.81 | CYP17A1 (0.42) | NAMPTMETAP1CYP17A1RAB9AATR | |
| SCHEMBL23770979 | 0.80 | NAMPT (0.50) | NAMPTCYP17A1RAB9AATRJAK2 | |
| SCHEMBL30196114 | 0.80 | NAMPT (0.50) | NAMPTCYP17A1RAB9AATRJAK2 | |
| SCHEMBL29394473 | 0.80 | LCK (0.47) | NAMPTMETAP1RAB9AMEN1NPC1 | |
| SCHEMBL222110 | 0.79 | NPC1 (0.58) | RAB9AMEN1NPC1GAAKMT2A | |
| SCHEMBL29695306 | 0.79 | NPC1 (0.58) | RAB9AMEN1NPC1GAAKMT2A | |
| SCHEMBL21743166 | 0.78 | L3MBTL1 (0.47) | FFAR2RAB9AGOT1SIRT2NPC1 | |
| SCHEMBL1012144 | 0.77 | KMT2A (0.53) | FFAR2RAB9AGOT1NPC1GAA | |
| SCHEMBL22523913 | 0.77 | LCK (0.43) | NAMPTMETAP1CYP17A1RAB9AATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118451068-A | Tri-fused ring derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |