Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28840093 | 1.00 | LMNA (0.45) | LMNAPTPN1ADORA3BRPF1CREBBP | |
| SCHEMBL28840089 | 1.00 | LMNA (0.45) | LMNAPTPN1ADORA3BRPF1CREBBP | |
| SCHEMBL28840106 | 0.86 | ALDH1A1 (0.48) | PTPN1BRPF1CREBBPBRD4ALDH1A1 | |
| SCHEMBL31039932 | 0.86 | ALDH1A1 (0.48) | PTPN1BRPF1CREBBPBRD4ALDH1A1 | |
| SCHEMBL28840104 | 0.86 | ALDH1A1 (0.48) | PTPN1BRPF1CREBBPBRD4ALDH1A1 | |
| SCHEMBL28840652 | 0.83 | POLB (0.49) | BRD4ALDH1A1MAPTHTTGAA | |
| SCHEMBL31039937 | 0.83 | POLB (0.49) | BRD4ALDH1A1MAPTHTTGAA | |
| SCHEMBL28840086 | 0.83 | ALDH1A1 (0.46) | LMNAPTPN1BRPF1CREBBPBRD4 | |
| SCHEMBL31039935 | 0.83 | ALDH1A1 (0.46) | LMNAPTPN1BRPF1CREBBPBRD4 | |
| SCHEMBL28840090 | 0.83 | ALDH1A1 (0.46) | LMNAPTPN1BRPF1CREBBPBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907277-B | Quinoxalinone asymmetric hydrogenation process | 哈尔滨工业大学（深圳） | 2024-08-06 | — | — | CN | disclosed |