Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1981891 | 1.00 | GRM5 (0.33) | GRM5CYP1A1CYP1A2CYP1B1CHRNB4 | |
| SCHEMBL8005775 | 0.84 | GRM5 (0.42) | GRM5CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL22202971 | 0.80 | CHRNB4 (0.31) | GRM5CHRNB4CHRNA3 | |
| SCHEMBL22202973 | 0.78 | GRM5 (0.31) | GRM5 | |
| SCHEMBL3346166 | 0.78 | GRM5 (0.34) | GRM5CHRNB4CHRNA3 | |
| SCHEMBL22202974 | 0.76 | CA12 (0.30) | GRM5 | |
| SCHEMBL1979138 | 0.74 | TTR (0.40) | GRM5 | |
| SCHEMBL27574747 | 0.73 | CHRNB4 (0.32) | CHRNB4CHRNA3 | |
| SCHEMBL419288 | 0.73 | MEN1 (0.43) | GRM5 | |
| SCHEMBL504770 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4703359-A1 | IMIDAZOPYRIDINE OR IMIDAZOPYRAZINE COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Simr Biotechnology Co., Ltd. (CN) | 2026-03-04 | — | — | EP | disclosed |
| WO-2024222712-A1 | IMIDAZOPYRIDINE OR IMIDAZOPYRAZINE COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海赛默罗生物科技有限公司 | 2024-10-31 | — | — | WO | disclosed |
| CN-118515663-A | Imidazopyridine or imidazopyrazine compounds, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2024-08-20 | — | — | CN | disclosed |