Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18704185 | 0.86 | LOX (0.31) | — | |
| SCHEMBL852757 | 0.86 | GRM5 (0.43) | GRM5 | |
| SCHEMBL31040201 | 0.78 | GRM5 (0.33) | GRM5CHRNB4CHRNA3 | |
| SCHEMBL1981891 | 0.78 | GRM5 (0.33) | GRM5CHRNB4CHRNA3 | |
| SCHEMBL31242533 | 0.77 | CA12 (0.44) | GRM5 | |
| SCHEMBL2767368 | 0.77 | GRM5 (0.50) | GRM5 | |
| SCHEMBL31242414 | 0.77 | GRM5 (0.50) | GRM5 | |
| SCHEMBL19781323 | 0.76 | KDM1A (0.34) | — | |
| SCHEMBL22202971 | 0.75 | CHRNB4 (0.31) | GRM5CHRNB4CHRNA3 | |
| SCHEMBL29937387 | 0.74 | LOX (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |