Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CPN1 | P15169 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454131 | 0.90 | NAAA (0.45) | NAAASMN1; SMN2SLC6A1TSHRSLC6A11 | |
| SCHEMBL7457705 | 0.90 | NAAA (0.45) | NAAASMN1; SMN2SLC6A1TSHRSLC6A11 | |
| SCHEMBL7457710 | 0.90 | NAAA (0.45) | NAAASMN1; SMN2SLC6A1TSHRSLC6A11 | |
| Hydrochloric Acid SCHEMBL6102499 | 0.88 | NAAA (0.44) | NAAASMN1; SMN2SLC6A1TSHRSLC6A11 | |
| Hydrochloric Acid SCHEMBL7455941 | 0.88 | NAAA (0.44) | NAAASMN1; SMN2SLC6A1TSHRSLC6A11 | |
| Hydrochloric Acid SCHEMBL7455934 | 0.88 | NAAA (0.44) | NAAASMN1; SMN2SLC6A1TSHRSLC6A11 | |
| SCHEMBL15565100 | 0.86 | NAAA (0.41) | NAAASMN1; SMN2SLC6A1TSHRSLC6A11 | |
| SCHEMBL14925177 | 0.80 | NAAA (0.54) | NAAASMN1; SMN2EPHX1 | |
| SCHEMBL2433610 | 0.80 | NAAA (0.67) | NAAASMN1; SMN2TSHRLMNAALDH1A1 | |
| SCHEMBL1695592 | 0.80 | NAAA (0.72) | NAAASMN1; SMN2TSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513422-B2 | Piperidine derivative | ASTELLAS PHARMA INC. (JP) | 2013-08-20 | — | — | US | disclosed |
| EP-2181990-B1 | PIPERIDINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2012-08-08 | — | — | EP | disclosed |
| US-20100256189-A1 | PIPERIDINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
| EP-2181990-A1 | PIPERIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2010-05-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256189-A1 | PIPERIDINE DERIVATIVE | AR, NR5A1, CYP17A1 | NAAA 1671/4885SMN1; SMN2 4547/4885SLC6A1 2260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.