Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.35 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.35 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457710 | 1.00 | NAAA (0.45) | NAAAALDH1A1TSHRCHRM1SLC6A1 | |
| SCHEMBL7454131 | 1.00 | NAAA (0.45) | NAAAALDH1A1TSHRCHRM1SLC6A1 | |
| Hydrochloric Acid SCHEMBL7455934 | 0.98 | NAAA (0.44) | NAAAALDH1A1TSHRCHRM1SLC6A1 | |
| Hydrochloric Acid SCHEMBL7455941 | 0.98 | NAAA (0.44) | NAAAALDH1A1TSHRCHRM1SLC6A1 | |
| Hydrochloric Acid SCHEMBL6102499 | 0.98 | NAAA (0.44) | NAAAALDH1A1TSHRCHRM1SLC6A1 | |
| SCHEMBL14925177 | 0.90 | NAAA (0.54) | NAAACHRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL3104069 | 0.90 | NAAA (0.50) | NAAAALDH1A1TSHRSLC6A1SLC6A11 | |
| SCHEMBL3111263 | 0.89 | NAAA (0.51) | NAAAALDH1A1GNAI3GNAO1GNAI1 | |
| SCHEMBL28256858 | 0.88 | NAAA (0.61) | NAAAGNAI3GNAO1GNAI1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27604463 | 0.87 | NAAA (0.50) | NAAAALDH1A1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101001854-A | Highly selective novel amidation method | TAKEDA PHARMACEUTICAL (JP) | 2007-07-18 | — | — | CN | disclosed |
| CN-1133637-C | Immunosuppressive compounds and methods | �꼪 | 2004-01-07 | — | — | CN | disclosed |
| EP-0900787-B1 | PROCESS FOR PREPARING PYRROLIDINE DERIVATIVES | KANEKA CORP (JP) | 2002-09-11 | — | — | EP | disclosed |
| CN-1246121-A | Immunosuppressive compounds and methods | PHARMAGENESIS INC (US) | 2000-03-01 | — | — | CN | disclosed |
| US-6005119-A | Process for preparing pyrrolidine derivatives | KANEKA CORPORATION (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0900787-A1 | PROCESS FOR PREPARING PYRROLIDINE DERIVATIVES | KANEKA CORPORATION (JP) | 1999-03-10 | — | — | EP | disclosed |