Clofenamide

Clofenamide

SCHEMBL310408

NS(=O)(=O)c1ccc(Cl)c(S(N)(=O)=O)c1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 12/20 0.59
CA2 P00918 12/20 0.59
CA9 Q16790 8/20 0.59
CA12 O43570 5/20 0.59
CA4 P22748 4/20 0.59
CA6 P23280 4/20 0.59
CA5A P35218 4/20 0.59
CA7 P43166 4/20 0.59
CA14 Q9ULX7 4/20 0.59
CA5B Q9Y2D0 4/20 0.59
CA13 Q8N1Q1 2/20 0.59
APEX1 P27695 2/20 0.59
POLB P06746 2/20 0.59
LMNA P02545 2/20 0.59
CYP2C9 P11712 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
VCAM1 P19320 1/20 0.56
CA3 P07451 2/20 0.52
CYP2C19 P33261 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Clofenamide SCHEMBL30748198 1.00 CA1 (0.59) CA1CA2CA9CA12CA4
Clofenamide SCHEMBL27524784 0.98 CA1 (0.57) CA1CA2CA9CA12CA4
Clofenamide SCHEMBL28383730 0.98 CA1 (0.57) CA1CA2CA9CA12CA4
Clofenamide SCHEMBL28282642 0.91 CA1 (0.50) CA1CA2CA9CA12CA4
SCHEMBL17478768 0.88 CA2 (0.55) CA1CA2CA9CA12CA4
SCHEMBL2980221 0.88 CA1 (0.50) CA1CA2CA9CA12CA4
SCHEMBL11009995 0.86 LMNA (0.51) CA1CA2CA9CA12CA4
SCHEMBL11010701 0.83 CA1 (0.46) CA1CA2CA9CA12CA4
SCHEMBL793608 0.82 CA2 (0.69) CA1CA2CA9CA12CA4
SCHEMBL25088037 0.81 CA2 (0.53) CA1CA2CA9CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2132 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075410-A Dry powder composition for intranasal delivery 2026-05-26 CN claimed
US-20250057876-A1 METHODS FOR TREATING AND/OR PREVENTING LYMPHANGIOGENESIS-ASSOCIATED DISEASES BY USING GOLD NANOCLUSTERS GOLDRED NANOBIOTECH CO., LTD. (TW) 2025-02-20 US claimed
US-20230381161-A1 COMPOSITIONS FOR THE TREATMENT OF HYPERTENSION The George Institute for Global Health (AU) 2023-11-30 US claimed
CN-116660426-B Method for rapidly determining various pesticide veterinary drug residues in animal-derived food and application 山东杰诺检测服务有限公司 2023-10-20 CN claimed
WO-2023183932-A2 MONOBODIES BINDING TO INTERCELLULAR ADHESION MOLECULE 2 (ICAM-2) NEW YORK UNIVERSITY (US) 2023-09-28 WO claimed
CN-116603066-A Composition for treating hypertension 乔治全球健康研究院 2023-08-18 CN claimed
CN-116327958-A Composition for treating hypertension 乔治全球健康研究院 2023-06-27 CN claimed
US-20230134747-A1 COMPOSITIONS FOR THE TREATMENT OF AUTISM SPECTRUM DISORDER STALICLA SA (CH) 2023-05-04 US claimed
US-20230125076-A1 COMPOSITIONS FOR THE TREATMENT OF HYPERTENSION The George Institute for Global Health (AU) 2023-04-27 US claimed
CN-115811974-A Compositions for treating autism spectrum disorders 斯塔利克拉股份有限公司 2023-03-17 CN claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
CN-1258254-A container for a transport container A & R INTERMODAL CORP (US) 2000-06-28 CN claimed
EP-0973656-A1 A VESSEL FOR A SHIPPING CONTAINER Bedeker, James E. (US) 2000-01-26 EP claimed
WO-1998045139-A1 A VESSEL FOR A SHIPPING CONTAINER BEDEKER JAMES E (US) 1998-10-15 WO claimed
US-5811547-A Method for inducing crystalline state transition in medicinal substance NIPPON SHINYAJU CO., LTD. (JP) 1998-09-22 US claimed
US-5700410-A Method of manufacturing wax matrices NIPPON SHINYAKU CO., LTD. (JP) 1997-12-23 US claimed
EP-0580860-B1 METHOD OF MANUFACTURING SOLID DISPERSION NIPPON SHINYAKU CO LTD (JP) 1997-10-22 EP claimed
US-4855289-A Combination of two active substances WESTER PER O (SE) 1989-08-08 US claimed