Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 3/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3107690 | 0.91 | FOLH1 (0.33) | CYP1A2CYP2C19CYP2D6RAB9ANPC1 | |
| SCHEMBL5246279 | 0.91 | RAB9A (0.40) | CYP1A2CYP2C19CYP2D6RAB9ANPC1 | |
| SCHEMBL3112810 | 0.90 | MLYCD (0.36) | RAB9ANPC1SMN1; SMN2MLYCDFOLH1 | |
| SCHEMBL3112218 | 0.89 | RAB9A (0.36) | CYP1A2CYP2C19CYP2D6RAB9ANPC1 | |
| SCHEMBL3106801 | 0.89 | HDAC4 (0.35) | CYP1A2CYP2C19CYP2D6RAB9ANPC1 | |
| SCHEMBL5245108 | 0.89 | NPC1 (0.37) | CYP1A2CYP2C19CYP2D6RAB9ANPC1 | |
| SCHEMBL3113751 | 0.89 | HPGD (0.41) | CYP1A2CYP2C19RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5249369 | 0.88 | MLYCD (0.36) | RAB9ANPC1SMN1; SMN2MLYCDFOLH1 | |
| Hydrochloric Acid SCHEMBL3117680 | 0.88 | MEN1 (0.37) | CYP1A2CYP2C19CYP2D6RAB9ANPC1 | |
| SCHEMBL5247710 | 0.88 | NPC1 (0.36) | CYP1A2CYP2C19CYP2D6RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803822-B2 | Triazole derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-28 | — | — | US | disclosed |
| US-20090105253-A1 | Triazole Derivative and Use Thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-23 | — | — | US | disclosed |
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105253-A1 | Triazole Derivative and Use Thereof | F2R, HRH4, F2RL3 | CYP1A2 418/4885CYP2C19 334/4885CYP2D6 1041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.