Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 6/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31043004 | 0.87 | P2RX7 (0.42) | STSMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL31165545 | 0.80 | STS (0.47) | STSGPR119MEN1KMT2ANPC1 | |
| SCHEMBL24762239 | 0.79 | STS (0.51) | STSGPR119MMP13 | |
| SCHEMBL23165563 | 0.79 | STS (0.42) | STSGPR119MEN1KMT2A | |
| SCHEMBL22797037 | 0.76 | PTPN2 (0.62) | STSKMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL31043013 | 0.76 | STS (0.53) | STSGPR119KMT2ANPC1ALDH1A1 | |
| SCHEMBL5266887 | 0.76 | GPR119 (0.65) | STSGPR119 | |
| SCHEMBL29079806 | 0.76 | GPR119 (0.46) | STSGPR119MEN1KMT2ANPC1 | |
| SCHEMBL34461283 | 0.76 | GPR119 (0.53) | GPR119MAPTPTPN2PTPN1PTPN6 | |
| SCHEMBL15475871 | 0.75 | KDM4E (0.48) | STSGPR119NPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658644-A1 | 2-(PYRIDAZIN-3-YL)-5-(TRIFLUOROMETHYL)PHENOLS AS NLRP3 INHIBITORS | Janssen Pharmaceutica NV (BE) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024160690-A1 | 2-(PYRIDAZIN-3-YL)-5-(TRIFLUOROMETHYL)PHENOLS AS NLRP3 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-08-08 | — | — | WO | disclosed |