Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31044749 | 1.00 | PIK3CD (0.50) | PIK3CDUSP30GPR119PIK3CAPIK3CB | |
| SCHEMBL31044638 | 0.93 | GPR119 (0.55) | GPR119 | |
| SCHEMBL30234630 | 0.91 | GPR119 (0.52) | PIK3CDUSP30GPR119PIK3CAPIK3CB | |
| SCHEMBL1698614 | 0.91 | GPR119 (0.52) | PIK3CDUSP30GPR119PIK3CAPIK3CB | |
| SCHEMBL25604586 | 0.91 | GPR119 (0.52) | PIK3CDUSP30GPR119PIK3CAPIK3CB | |
| SCHEMBL31044549 | 0.91 | USP30 (0.44) | PIK3CDUSP30GPR119 | |
| SCHEMBL25282448 | 0.89 | GPR119 (0.54) | PIK3CDUSP30GPR119PIK3CAPIK3CB | |
| SCHEMBL29212746 | 0.89 | GPR119 (0.54) | PIK3CDUSP30GPR119PIK3CAPIK3CB | |
| SCHEMBL25191966 | 0.89 | GPR119 (0.54) | PIK3CDUSP30GPR119PIK3CAPIK3CB | |
| SCHEMBL31552861 | 0.89 | GPR119 (0.54) | PIK3CDUSP30GPR119PIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285874-B | RET inhibitor, pharmaceutical composition thereof and application thereof | 广东东阳光药业股份有限公司 | 2024-08-09 | — | — | CN | disclosed |