Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31044636 | 0.91 | PIK3CD (0.50) | USP30GPR119PIK3CD | |
| SCHEMBL31044749 | 0.91 | PIK3CD (0.50) | USP30GPR119PIK3CD | |
| SCHEMBL1698892 | 0.90 | GPR119 (0.48) | USP30GPR119EPHX2PIK3CD | |
| SCHEMBL30019202 | 0.88 | GPR119 (0.50) | USP30GPR119EPHX2 | |
| SCHEMBL31044638 | 0.88 | GPR119 (0.55) | GPR119 | |
| SCHEMBL25093966 | 0.88 | GPR119 (0.50) | USP30GPR119EPHX2 | |
| SCHEMBL25093965 | 0.87 | PARP1 (0.48) | USP30GPR119EPHX2 | |
| SCHEMBL31178523 | 0.87 | PARP1 (0.48) | USP30GPR119EPHX2 | |
| SCHEMBL12523843 | 0.85 | MEN1 (0.43) | USP30GPR119EPHX2PIK3CD | |
| SCHEMBL25193220 | 0.84 | USP30 (0.54) | USP30GPR119EPHX2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113683611-B | Novel RET inhibitors, pharmaceutical compositions thereof and uses thereof | 广东东阳光药业股份有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-111285873-B | RET inhibitor, pharmaceutical composition thereof and application thereof | 广东东阳光药业股份有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-111285874-B | RET inhibitor, pharmaceutical composition thereof and application thereof | 广东东阳光药业股份有限公司 | 2024-08-09 | — | — | CN | disclosed |