SCHEMBL310448

SCHEMBL310448

C=C(C)C(=O)Oc1ccc(C=C(C#N)C(=O)O)cc1

nearest known ligand 0.65

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.55
CISD1 Q9NZ45 1/20 0.55
KDM4E B2RXH2 1/20 0.55
SLC16A3 O15427 1/20 0.55
ALDH1A1 P00352 1/20 0.55
CYP3A4 P08684 1/20 0.55
HPGD P15428 1/20 0.55
SLC16A1 P53985 1/20 0.55
GPR35 Q9HC97 1/20 0.55
ELANE P08246 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14378641 1.00 EGFR (0.55) EGFRCISD1KDM4ESLC16A3ALDH1A1
SCHEMBL310447 1.00 EGFR (0.55) EGFRCISD1KDM4ESLC16A3ALDH1A1
SCHEMBL9365545 0.85 EGFR (0.61) EGFRCISD1KDM4ESLC16A3ALDH1A1
SCHEMBL9365540 0.85 EGFR (0.61) EGFRCISD1KDM4ESLC16A3ALDH1A1
SCHEMBL13919924 0.84 ALDH1A1 (0.62) KDM4EALDH1A1HPGD
SCHEMBL13037033 0.84 MAPT (0.57) EGFRCISD1KDM4EALDH1A1CYP3A4
SCHEMBL8965681 0.82 ALDH1A1 (0.50) EGFRKDM4EALDH1A1CYP3A4HPGD
SCHEMBL28093619 0.82 ALDH1A1 (0.74) EGFRCISD1KDM4ESLC16A3ALDH1A1
SCHEMBL5550763 0.81 EGFR (0.59) EGFRCISD1KDM4ESLC16A3ALDH1A1
SCHEMBL11369353 0.81 EGFR (0.59) EGFRCISD1KDM4ESLC16A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1481244-A2 MONOMERS AND POLYMERS HAVING ENERGY ABSORBING MOIETIES OF USE IN DESORPTION/IONIZATION OF ANALYTES Ciphergen Biosystems, Inc. (US) 2004-12-01 EP claimed
US-20030207462-A1 Monomers and polymers having energy absorbing moieties of use in desorption/ionization of analytes CIPHERGEN BIOSYSTEMS, INC. 2003-11-06 US claimed
US-20030207460-A1 Monomers and polymers having energy absorbing moieties of use in desorption/ionization of analytes CIPHERGEN BIOSYSTEMS, INC. 2003-11-06 US claimed
WO-2003064594-A2 MONOMERS AND POLYMERS HAVING ENERGY ABSORBING MOIETIES OF USE IN DESORPTION/IONIZATION OF ANALYTES CIPHERGEN BIOSYSTEMS, INC. (US) 2003-08-07 WO claimed
US-20230233645-A1 EFFECTIVE TREATMENTS FOR VASCULAR ASSOCIATED MACULOPATHY, SEVERE MACULOPATHY, LATE-STAGE MACULOPATHY, AND ABERRANT CHORIOCAPILLARIS UNIV UTAH RES FOUND (US) 2023-07-27 US disclosed
EP-4185301-A1 COMPOSITIONS AND METHODS FOR DETECTING AND TREATING HIGH GRADE SUBTYPES OF UTERINE CANCER The Regents Of The University Of Michigan (US) 2023-05-31 EP disclosed
US-20220317126-A1 BIOMARKERS FOR OVARIAN CANCER CTAP3-RELATED PROTEINS ASPIRA WOMEN'S HEALTH INC. (US) 2022-10-06 US disclosed
US-11371993-B2 Autoantibody biomarkers of ovarian cancer ADELAIDE RESEARCH & INNOVATION PTY LTD (AU) 2022-06-28 US disclosed
CN-105823877-B Biomarkers for ovarian cancer: CTAP 3-related protein 约翰·霍普金斯大学 2022-02-25 CN disclosed
US-11255857-B2 Biomarkers for ovarian cancer CTAP3-related proteins ASPIRA WOMEN'S HEALTH INC. (US) 2022-02-22 US disclosed
WO-2022020359-A1 COMPOSITIONS AND METHODS FOR DETECTING AND TREATING HIGH GRADE SUBTYPES OF UTERINE CANCER THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2022-01-27 WO disclosed
US-20210353712-A1 METHODS OF DIAGNOSING AND TREATING VASCULAR ASSOCIATED MACULOPATHY AND SYMPTOMS THEREOF UNIV UTAH RES FOUND (US) 2021-11-18 US disclosed
US-20040029191-A1 Detection of kinase substrates and products using ion mass spectrometry CIPHERGEN BIOSYSTEMS, INC. 2004-02-12 US disclosed
WO-2004009798-A2 PROTEIN INTERACTION DIFFERENCE MAPPING CIPHERGEN BIOSYSTEMS, INC. (US) 2004-01-29 WO disclosed
WO-2003102542-A2 COMPARATIVE PROTEOMICS OF PROGRESSOR AND NONPROGRESSOR POPULATIONS CIPHERGEN BIOSYSTEMS, INC. (US) 2003-12-11 WO disclosed
WO-2003101394-A2 DEFENSINS: USE AS ANTIVIRAL AGENTS CIPHERGEN BIOSYSTEMS, INC. (US) 2003-12-11 WO disclosed
WO-2003097867-A1 DETECTION OF KINASE SUBSTRATES AND PRODUCTS USING ION MASS SPECTROMETRY CIPHERGEN BIOSYSTEMS, INC. (US) 2003-11-27 WO disclosed
US-20030207462-A1 Monomers and polymers having energy absorbing moieties of use in desorption/ionization of analytes CIPHERGEN BIOSYSTEMS, INC. 2003-11-06 US disclosed
US-20030207460-A1 Monomers and polymers having energy absorbing moieties of use in desorption/ionization of analytes CIPHERGEN BIOSYSTEMS, INC. 2003-11-06 US disclosed
WO-2003064594-A2 MONOMERS AND POLYMERS HAVING ENERGY ABSORBING MOIETIES OF USE IN DESORPTION/IONIZATION OF ANALYTES CIPHERGEN BIOSYSTEMS, INC. (US) 2003-08-07 WO disclosed