Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31045186 | 0.97 | CYP3A4 (0.41) | KCNH2CYP3A4CNR2NPC1GALR3 | |
| SCHEMBL31044939 | 0.90 | KCNH2 (0.41) | KCNH2CYP3A4CNR2NPC1GALR3 | |
| SCHEMBL31044854 | 0.89 | KCNH2 (0.41) | KCNH2CYP3A4CNR2NPC1GALR3 | |
| SCHEMBL29990942 | 0.89 | KCNH2 (0.40) | KCNH2CYP3A4CNR2NPC1GALR3 | |
| SCHEMBL31045174 | 0.89 | KCNH2 (0.40) | KCNH2CYP3A4CNR2NPC1GALR3 | |
| SCHEMBL31044907 | 0.88 | CNR2 (0.43) | KCNH2CYP3A4CNR2NPC1GALR3 | |
| SCHEMBL31045078 | 0.88 | KCNH2 (0.40) | KCNH2CYP3A4CNR2NPC1GALR3 | |
| SCHEMBL31044809 | 0.88 | KCNH2 (0.40) | KCNH2CYP3A4CNR2NPC1GALR3 | |
| SCHEMBL31045122 | 0.87 | NPC1 (0.39) | CYP3A4NPC1GALR3NR2F2RAB9A | |
| SCHEMBL31044882 | 0.87 | FLT3 (0.44) | KCNH2CYP3A4CNR2NPC1GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240279236-A1 | COMPOUNDS AND METHODS OF TREATING TUBERCULOSIS | FIMBRION THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279236-A1 | COMPOUNDS AND METHODS OF TREATING TUBERCULOSIS | G6PD, SDHA, NQO1 | KCNH2 4421/4885CYP3A4 1533/4885CNR2 3384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.